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Lighting up the Light of Memory for Alzheimer's Disease

Date：2025-03-11 16:39 Source：未知 Editer：admin

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In the long haze of Alzheimers disease, an 80 year old man has ushered in the dawn. Recently, this patient who has been diagnosed with Alzheimers disease for 6 years successfully underwent deep neck lymphatic venous anastomosis (LVA) at Bei...

In the long haze of Alzheimer's disease, an 80 year old man has ushered in the dawn. Recently, this patient who has been diagnosed with Alzheimer's disease for 6 years successfully underwent "deep neck lymphatic venous anastomosis" (LVA) at Beijing Aviation General Hospital. After the surgery, his cognitive function improved significantly, his memory also improved significantly, and his ability to take care of himself gradually recovered, bringing new hope to patients and their families who have suffered from pain and suffering.
Suffering from illness: The heavy burden of Alzheimer's disease
Six years ago, this elderly person was diagnosed with Alzheimer's disease. Afterwards, the condition gradually worsened, with symptoms such as irritability, anxiety and depression, decreased memory function, and speech disorder. Sleep increased, and the ability to take care of oneself was severely limited, causing great pain to both the patient and their family. After detailed evaluation and examination, the Department of Neurosurgery at the Aviation General Hospital has confirmed that the elderly person is in the moderate to severe stage of Alzheimer's disease. In the face of this difficult disease, traditional drug treatment has limited effectiveness and the progression of the condition is difficult to effectively control.
Innovation breakthrough: LVA surgery opens up a new path
In order to seek more effective treatment options, a multidisciplinary team from the Neurosurgery, Neurology, Anesthesiology, Cardiovascular Medicine, Respiratory and Critical Care Medicine departments of the Aviation General Hospital jointly evaluated and rigorously screened biomarkers, ultimately developing a personalized surgical plan for the patient called "Cervical Deep Lymphatic Venous anastomosis Surgery".
Xing Yan, Vice Chairman and Secretary General of the Neurodegenerative Disease Professional Committee of the Chinese Microcirculation Society, and Director of the Department of Neurology at the Aviation General Hospital, pointed out that Alzheimer's disease is a complex neurodegenerative disease, and traditional treatment methods mainly rely on drugs, but the efficacy is limited, especially in moderate to severe patients, and the progression of the disease is difficult to effectively control. The emergence of LVA surgery provides a new approach for the treatment of Alzheimer's disease and is expected to become an important supplement to traditional drug therapy.
Wang Lin, director of the Department of Neurosurgery at the Aviation General Hospital, introduced that Alzheimer's disease is closely related to abnormal deposition of beta amyloid and tau proteins in the brain, and the core mechanism is the dysfunction of the brain lymphatic system leading to a decrease in toxin clearance ability. Starting from the pathological mechanism, the "deep neck lymphatic venous anastomosis" directly addresses the core issue of "cerebral endotoxin accumulation". By establishing a anastomosis channel between lymphatic vessels and veins in the neck, improving cerebrospinal fluid lymphatic drainage, reducing intracranial pressure, promoting the excretion of pathogenic proteins, and thus delaying or even reversing disease progression, it provides the possibility of surgical intervention for patients in the middle to late stages.
Significant results: Significant improvement in patients' quality of life
According to data from multiple centers in China, after undergoing "deep neck lymphatic venous anastomosis", patients' scores on the Brief Mental State Scale increased by 30% -50%, and some patients' cognitive function improved significantly compared to preoperative levels. The patient can resume activities the day after surgery, and the hospitalization period is shortened to 5-7 days. This not only greatly improves the quality of life of patients, but also alleviates the pressure on families and society to a certain extent.
Future Outlook: Continuous Exploration and Multidisciplinary Collaboration
Although LVA surgery has shown exciting therapeutic effects, Xing Yan reminds that the surgery is still in the clinical exploration stage, and its long-term efficacy and scope of application still need further verification. More clinical research and case accumulation are needed in the future, combined with basic research, to clarify the optimal indications for surgery, optimize surgical procedures, and further reduce surgical risks.
In addition, the deep collaboration model between the neurology and neurosurgery departments of the Aviation General Hospital also provides useful reference for the comprehensive treatment of other complex diseases. Through interdisciplinary joint research and development, it is expected to find new treatment methods for more difficult diseases and bring more hope to patients.
The road to treating Alzheimer's disease is still long, but the emergence of "cervical deep lymphatic venous anastomosis" undoubtedly lights up a bright light in this field and brings new hope to patients and their families. With the continuous deepening of medical research and the continuous exploration of clinical practice, we believe that there will be more effective treatment methods in the future to help more patients overcome the disease and regain the light of memory.
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